Just created a new Wordpress_MU on latest version of wordpress on hxxp://mininicheblog.com I followed the right procedure as shown here hxxttp://codex.wordpress.org/Create_A_Network Everything shows up but when I create a new Sub-domains, the url doesn't load up first. After few hours it shows a blank page of index of /..... What I suppose if in WP_MU when we create new Sub-domain all the plugins, wp files, themes has to be also loaded on these sub-domain right. Also on accessing from my cPanel, I get to see all these Sub-domains folders on public_html folder and not inside hxxp://mininicheblog.com folder. PLEASE HELP ME OUT BUDDIES ....
Make sure you setup wildcard subdomains. Goto your cpanel -> subdomains -> create a subdomain like hxxp://*.mininicheblog.com That will fix it
This is because initially your DNS don't propagate, then it happen and it point to blank directory instead of your WordPress Installation directory. Let me know if, i could personally resolve this
Your sub-domain hxxp://*.mininicheblog.com should be pointed to root folder of the main domain (mininicheblog.com)