What like RFK? Shot by Sirhan Sirhan in June 1968, that Muslim terrorist via the order of Yasser Arafat as retaliation for the June 1967 six-day war. The Kennedy's just always found themselves on the wrong end of a gun barrel.
Sirhan Sirhan had nothing to do with... But what latehorn meant is that all their male descendants died in suspicious circumstances and none of natural causes.
damn, beat me to it anyway, i voted 'Not Oswald' as according to Robot Chicken, it was a ferret, as they are nature's deadly assassins