Who have this email data/list and doing emailing? Female market US targeted 18+ years old Welcome to leave a message here
Sending spam is the worst type of advertising...and most ISPs have close port 25 so the chance of sending spam is very small... There are better ways than sending spam
go find blogs/websites that cater to women needs and talk to the webmaster and see if you can get a partner deal and send your offer in their newsletter.. it will not be cheap though