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There are lots of alternatives as other members have already mentioned. But, which ad network works for which site can only be known by testing different ad networks on your site. Feel free to test different networks for a few days and you'll see which gives you the most income.
frankly speaking, adsense is one of the best account for earning. none is required other than adsense, if you are - dedicated with faithhful afforts in adsence, - invest sufficient time towards adsence, - give preference it as important, etc. its helps you alot to earn sufficient or you can also use as substitutes like (i.e) infolinks Yahoo/Bing Network Media.net MadAdsmedia.com etc. that can also help you to earn more but according to me,adsence helps you for earning money that you desired. hope for best. good luck mate.