Depends what kind of site and traffic you have. Is your traffic looking to buy something? Are they teenagers?
This really is more of a question of affiliate vs adsense. look at your adsense ads... do they goto affiliate offers? if so you can just cut out the middle man and go direct.
I would try it, but would not replace Adsense if it's doing quite well. You can use both on the same page, just don't overdue your site with ads.
You mentioned Azoogle is good for teenagers and products for sale? What niches is it strong for? Real Estate?
azoogle is great....if you have the right traffic and visitors. If not then stick with Adsense otherwise you could end up loosing your revenue rather than generating alot more.
If you have natural traffic from teenagers, are there any obvious azoogle product categories that work particularly well, other than ringtones? Thanks!