You can get nice CTRs if you let your traffic comes naturally through organic search. CTRs will go down the drain if you do Diggings or submit your contents to social bookmarking sites. Let those who really have interest in what you have come to you, do not invite curious visitors.
I beg to differ. Google really loves high CTRs because high CTRs made more money for them but you have to make sure that your high CTRs are legit and genuine. Free from click frauds, else you know what Google would do to your AdSense account.