I have a site that made quite nice job with Adsense – the average eCPM was over 25 euros. Then I made little little changes – move the adbox, changed colors and BOOM my eCPM have tripled since then. Must say it is amazing. So test your pages with different ads and different colors. I must say that I didn't first believe that the difference can be this big, but now I have to believe it. The average from bit over 25 euros to almost 90 euros, that is a big difference.
I don't use any ready theme, I just started to test different variations. The colors I'm using right now, are just contrary to the colors of my site, so the ads are really jumping out of my page. No, it doesn't look nice at all, but it works.
I made little comparison to the measurement month before and the results are amazing. These are my results from last week compared to the situation month before: AdSense revenue +177.15%, Adsense eCPM +362.86%, AdSense CTR +332.69%, AdSense Page Impressions -40.12%. Now I have to concentrate to the traffic.
TESTING is a seldom talked about key component for successful marketing. Testing everything...Testing offers for conversion before expending a lot of time and effort. Testing for more conversions...etc. Little changes can have big results. Good job Testing out your layout and congratulations on your results. Best Wishes