Personally, I use Genesis, it works okay and is quite easy, but can take a little while to get your head around it. Alternatively, most of my themes that I make for clients are instead built on Underscores (or _s for short), it's an open source project that gives you a blank theme to work with.
Thesis i think is a good choise, it works for me very well. Genesis is also a very coole and good framework
Hi, Some best Frameworks such as: Genesis, Headway ,Builder Framework or Thesis Theme... They are premium Framework, or you also can try free Framework at: http://www.smartaddons.com/wordpress/themes/item/475-ya-framework-responsive-wordpress-theme-framework Hopeful you find the best Framework.
I have been using Thesis theme Framework for a long time and I love it. with the new version you don't need any coding skill. You can create blog layouts simply dragging and dropping boxes, widgets etc. It seems a bit difficult to do things with Thesis, but once you understand it well you'll see that you can do wonderful things with this Framework. Hope this helps.