Does anyone do this? The idea is based on the value of clicks being lower during the night, pulling down the site, potentially leading to smart pricing. I don't know if some AdWords advertisers have a time block when they advertise each day, e.g., 9 - 5 p.m., or at some time they think visitors are serious traffic, although it seems like it. Even if they don't, the net result is virtually the same if they have daily budgets, which are usually met each day. Anyway, I'd like the equivalent option or Adsense match. The ability to switch off Adwords during the least profitable times of the day would be good to protect the integrity of the site from junk MFA ads which come out at night like bats out of hell. I don't foresee Google offering Adsensers the option from the Adsense control panel. But there is a simple workaround. It would require two sets of web pages: one with ads, one without. Then uploading daily, which is easy and fast enough with all files in one folder. Time: two minutes. My main site sees the value of clicks rise from about 8 a.m. each day until about 5 p.m., after which they go down steadily for the rest of the day... I wish Adsense stats showed hourly data with click value for that hour, but you can monitor it yourself.
Considering the large number of pages on my site it would probably be more than two minutes. A much easier solution is to use #includes for your ads. I do this, having about a dozen files (or so) in which I have the ad code for various color schemes and sizes of ads. All you would have to do is swap out those few files at certain times, replacing them with ones from a different ad network or just blank tables sized accordingly. The whole thing could be done from the crontab. Lot easier to switch a dozen files than hundreds or thousands depending upon your site size, plus if you edit any of your files you'd have to edit twice. It all depends upon your type of site, too. Some sites may get 24-hour traffic that is good, others may have peak times, you'd have to examine your traffic and revenue to get a better idea.