hi, The first ad that load in the web page and get the most click only $0.05 per click, should i block it?
impossible to tell you if you give no URL of site and thus all details of your site's content and volume / topics missing please give URL
You'd better not do that, because that's a possibility that you'll get cheaper ads after doing that.(i.e:you'll probably get lower CPM ads after blocking that)
I would not just block ads that pay less, because google is pretty good at getting the best ads (in cpm) on your site.
The first ad in the first block is going to be the highest paying - if you block it, the next highest paying ad moves into that position and it will be LESS than 5 cents. Unless it's a direct competitor that you don't want to show, don't block anything as Google will always deliver the best paying ads on it's own.
I used my ad filter for two months to block the cheap ads. As a result, my CTR went up, but my CPM and overall earnings went down. After the two months were over, I cleared my ad filter and my CTR went back down, but my CPM and earnings increased. It turns out that my ad filter was blocking a lot of CPM ads that were generating a nice portion of my earnings. I'd recommend not using the ad filter unless there is a specific competitor you wish to block.
you will never know the click value of the adsense ads. if you want to block mfa site , adsblacklist.com can help you
If you have more ads in one block then the first $0.05 per click ad is probably followed by lower paid ads anyway, so it will most probably just decrease your income rather than increase it.