I think, there are too many adsense ads there. 3 units is sufficient. Header, in the content (use feedflare from feedburner) and the sidebar will do. Additional of google custom search will be better.
Placement is fine, but the site on the wide screen it's a bit far on right... you could limit the site wideness.
Looks ok! You've got one ad in the golden triangle and a large block on route to the close-window button. Should be fine. I'd try reducing the width of your page a little though. Seems a bit too much white space. Users will probably find the page too empty. Funny, just blogged about this...
@john: thanks for replying man... @grg: Ok I will think of using a fixed width template, its at the moment at 100% width...