you must know what your niche is and go after the people that you think will bring in the bacon. first you must make real relationships. I you really have to be good at your game and do your home work.
This topic has been brought up time and time again, it's very simple. Go to Twitter profiles in your niche who have a lot of followers - generally at least 3 or 4 thousand, more is better. Then click their followers link and scroll through their list and add as many people as you want (don't exceed 500/day, Twitter will mark your account as spam). Continue this until you have a decent amount of followers
Twitter is going to help you only if you have genuine followers and also atleast 1000. And then keep tweeting daily with something exclusive. - Mr.President -
Yes, create real follower and genuine, the number is the secret, the bigger follower the more traffic you'll get
Never tweet over-advertising links on twitter. Trust me, people will stop following you because it is like extra spam they are reading, Only tweet links to useful information. And, follow other twitter members and they might follow you back. Also, I have another piece of useful information. Try to tweet things that many people search for on twitter so that they can find your tweets, and if they like them, then expect followers,