Mesothelioma is The Best Hight Paying Keyword

I think your intention was to make money through the rev share, but if thats not the case your wasting your time with this keyword anyway, too much competition, not much demand. As yfs1 said look for keywords with not much competition, reasonable search volume that pay ok.

Having only one keyword won't make your site "more optimal for the visitor" this makes no sense, for instance this forums optimized for search engine forum and webmaster forum, which is more then 1 keyword but still "optimal"

 

OK, I understood, many key words is very good.