From an SEO standpoint they are as good as any other domain extension. Personally I would choose a .com or .net instead though because from a marketing standpoint most people are familiar with .net and .com domain names, some potential site visitors may not know that .me is a legitimate tld.
I personally only find a .ME domain useful for a personal portfolio or as a word extention such as add.me etc. I see no point in choosing a .ME over .org, net, com if they're also available however.
For a common website that can reach out to a targeted audience, i would recommend a .com or .net extension.
.me is the best domain extension for personal brand name. .me domain extension setting Internet world records, as the fastest ever selling new domain extension. I believe it suitable for those professional people to use it like sales ppl , agent, CEO and celebrity that put strong own their personal brand name.
.me is gaining popularity but dont think I will choose them over .com .net .org unless its for personal branding or useful meaning like meet.me (sold for $450,000)
.me is good.. if you want to have a personal website, a portfolio, a specific service site like website designing, gfx work etc. its gaining popularity too..
I only own 1 .me sadly,well its a .me.uk from what I have been reading its a very good tld especially if its a one generic word. Go for it is what I think, and all the best.
I own about 15 .me domains. I have one in particular that I am looking to sell to the right person! Penpals.me