If I opt out of interest-based advertising on my site, will effect my adsense earnings. To opt out of ads based on user interest categories: 1. Sign in to your AdSense account. 2. Visit your My Account tab. 3. Go to the Account Settings page. 4. In the Interest-based Ads Preference section, click edit. 5. Select the button marked Do not show ads based on user interest categories and save your changes. Replay with your opinion.