Is their an advantage or dissadvantage to using Google Sites web page maker if i'm also going be using ADWords. It said something about scrubbing the URL for all web pages.
Depending on what type of page, product your promoting.. a lot of publishers offer free landing pages for their affiliates.. you should look into that.
Have a look at this guide > http://rapidshare.com/files/140013849/LANDING_PAGE_PROFIT_BOOSTER.PDF.html It has useful info about building landing pages for Adwords.
I don't think there is any advantage between using Google Page Maker and Adwords QS for your landing page. Its still the same HTML.