In the past 4 days alone, all other things being equal I've watched click through rates drop 80%. Soon they will be in the realm of untargeted ... oh wait, now they are in the realm of completely targeted Adbrite campaigns. I have no idea where they are pulling the completely mismatched ads from that are displaying on my sites which are very tight niches and heavily themed. Adsense on the other hand is still spot on with their target demographics on my sites. Will truly be interesting to see if Microsoft can play in the contextual advertising space. However Microsoft tends to have a very egocentric view and will likely dismiss the Affiliate Masses as they focus in on the same High Dollar Advertisers/Publishers everyone wants. There is money in numbers... Amazon has proved it.
ouch, time for another shakeup at Yahoo! Publishers will start turning to other systems soon. Luckily yahoo.com is pretty big ito traffic, hopefully that will keep the advertisers from jumping ship as well. A good thing they're not international.