I would say have a good look round the the forum theres lots of information on adsense on here, failing that have a look on ezine articles for some free information on it.
if you are new in this field than i would like to suggest you to take some beginner Tutorial about the basic of adsense and must read google policy guideline
You should give an attractive logo or theme and read out the posts daily in forums about making more money on adsense. And the Google is the best place as a guide.
I think you should gather some books and start reading up on the main ways to earn with adsense. There are tons of books on the subject and each of them can help. Visit other internet marketing forums and get advice there. You could also go the quick route and buy websites that are already earning with adsense via here and even on flippa.
Basically, the more targeted traffic you get to your site, the more $$$ you make. The key word here is "targeted". Placement of ads is really no secret. In my experience people love skyscraper ads in the sidebar, 160x600 is my best ad. The best place is the square 250x250 or the bigger ones in the middle of your articles so that it looks like its part of your content. I have found horizontal banners in the header get less clicks that the other two I mentioned. Make the placement of your ads look natural and not disruptive to your users. The way I like to think of it, you are providing resources to your users that are related to your niche. In return they get you money.
To make money with adsense you have to get traffic to your website. To get traffic to your website you have to have plenty of good original content.
First of all I want to ask, what do you know about building website.. Can you build website by yourself.. Can you pick a niche by yourself. If you can do this above things than next task is adding content to your site.. When good quality visitors comes to your website than you can add Adsense code in your website. So go with the process and follow.. I hope this helps..
Get yourself a good ctr theme such as adsense pro ultimate or magnum...many people have been using it and have reported good success
Search on Google - and read the DP old posts. You will have to read a lot to get the grasp of how you can make it big with Adsense - asking the questions wont help you much here.
Don't spend more than one week reading stuff here. When it comes to adsense; building and testing and tracking is paramount. READ and learn as much as you can for a week or so; then work, work hard!
one really important prerequisite for making money with Adsense is traffic. You might have an incredibly high CTR but if you don't manage to drive traffic to your site, you won't be making money.the most important free traffic source are search engines. traffic from search engines is targeted and as a rule it converts well.