That's the best option ! No need to scan pc - it's always clean I've 2 computers - one with NOD32 and second .. Ubuntu !
Make sure your copy of operating system has latest updates from the vendor, install an antivirus/spyware and keep it updated with latest virus definitions. Do not browse untrusted websites, also check for infected removable medias before you use them Disable autoruns in your system if it's windows.
Saying which anti-malware combination is best is a bit like saying what your favourite wine is...the next person will likely not agree. My opinion is Kaspersky & Spyware Doctor are the best paid combo whereas AVG and Superantispyware is the best free protection team.
if you ask me how I would say 1.dont connect to the internet. 2.dont install anything except original windows. 3.use other people's computers.