Google site targeting allows AdWords advertisers to target only the sites they want. Cost is on a CPM (cost-per-thousand impressions) basis. That CPM ad will compete against the CPC (cost-per-click) ads in the auction - and if it wins, it will run in place of the CPC ads that would have otherwise appeared. As an AdSense publisher, you would get paid for each impression on that ad, rather than for each click. So site targeting means more money. If a site-targeted ad (text or image) appears on my sites, it means that that ad is paying you more than any CPC ad that would appear in that ad unit. Now comes the obvious question; how do I get my site selected for a site targeted campaign? Believe it or not, this is not a hard question to answer. Here they are.