There does seem like a lot of bots run twitter now, but you can tell which is which. Real people respond to real people and if you can target your audience correctly using different strategies then you can make conversions. However, I have found that you much be REALLY consistent with tweeting adding followers, sending @ replies, Direct messages, etc. You can also try revtwt to make some money using twitter.
Stay updated be in touch with your clients in twitter, then would be giving you further work orders to you..
Confusing topic title is confusing :/ Should have a do in there somewhere. And a question mark. But I'm sure there is someway to earn direct money through Twitter. What about getting a job there?
first think about what you want to sell.. then create a username targeted for that and follow the followers of a guy that is promoting same niche as you do (he probably has the target audience)