How do you backup your websites?

I once had a catastrophic failure on my computer that destroyed my website data. Thank God I had a full backup (data, application, everything) on my other computer's hard drive.

 

I was using http://www.tech-pro.net/site-backup-cp.html to backup to my pc via windows schedule task every nigth.

Now, my server is backing up on server and offsite everynigth.

 

Carbonite looks excellent, I'm going to sign up for that as soon as I upgrade my HDD.