You may have seen this almost a year ago in the freebies section - I modified a hacked version (by Ran) of the 45n5 free eBay Amazon YouTube Adsense mashup script so you can make individual template pages with original content for little "mini-sites". There are all kinds of things you can do with this - you can even hack the script even more for your own needs. Works with current YouTube API and EPN, the eBay Partner Network, in addition to having caching and being really quick (thanks to Ran!) Check it out, you have nothing to lose - free niche site script.
Thanks JT, I'm just downloading it now to test it out and you might see me on your forums asking a few questions soon