Who shows sites in frames anymore? Javascript should handle it easily. Can you give an example of your site in a frame that you haven't been able to break out of?
You Didn't Get Me I Want To Say That When People Advertise in My Site It Shows In-side Frames ...! I Want That My Site Pop-out Frame
Some advertising systems use iframes, which is normal, if those are the frames you are concerned about. Don't do anything to the ads as it will probably violate their TOS.
That Is What I Want As Explained By @ryan_uk I Want That They Are Un-able To Advertise My Site On PTC Sites
OK, now I understand, I think. You don't want you site within a frame. So you would need to deny it via .htaccess with something like: Header set X-Frame-Options DENY Code (markup): IF you are using Apache, otherwise you will need to research the equivalent for whatever webserver you are using.
You could use JavaScript, but that is an easier to bypass method. Did you actually try searching Google for "break out of frame with javascript"? It's a well-documented solution.