Ok color me stupid but, why would you want to have ads that are relevant to your site when you are trying to keep people on your site? I mean it helps on clicks I agree, but your opening the door for you site members to go elsewhere for something you have on your site?? I use ad targeting to target other ads I think my users might like and it works for me, I do wish I could get a higher CTR (I would love to make $1000 a day) but atleast I know and hope I keep the ones coming to my site coming back... Could someone share some light on this??
Depends on what site you are talking about. If I have a lyrics site I sure wouldn't care if my visitors leave by clicking an ad, but if I have a site that sells expensive software I would rather keep them on my site and let them pick something to buy.