I took a peek at your site just now and I don't think I can help much since your site is a bit confusing. If you want to optimize AdSense ads on your site, you have to determine your link colors and overall site theme first. Once you have determined those two, you can then do the following: Optimize your AdSense ads and make sure that their link colors are well blended in with your overall site theme. Place block and link ads at the top of the fold as well as the bottom of your content like what you have done right now. Place Skyscraper block and small link ads in your sidebar. Good luck!