I own many arcade sites. All using YPN on all of them. I use different arcade scripts, all mostly with the same content. Whats weird is on a GameSiteScript arcade script, there are medical ads such as erectile dysfunction, seizures etc as well as some game ads. Like this site: arcademuffin.com and its the same rotation of ads for all scripts like this running YPN. Now on another script such as 4newbs.com the ads are VERY relevant. They get NO medical ads and only arcade related ads. I NEVER set targetting so that cant be it. The meta tags, keywords are the same. Im absolutley clueless! Anyone have any ideas? its so funny...every site running the "arcadesitescript" all show the same exact ads at the same times.
Remember that YPN is still in beta and Yahoo tends to show non-relevant ads to possibly test the advertiser's campaign. It has happened to me also.
Perhaps due to the nature of the programming there is higher keyword density in one script then the other for games and arcade.