B2B generally stands for business to business. That just means that you sell your product or service to businesses rather than individuals. Depending on what you are selling it can be a great way to go or a waste of time. Businesses tend to have bigger budgets, make larger orders, and are willing to pay more for quality. However, businesses tend to be more discerning so if your product is more hype than anything else you will have more trouble selling to businesses.