Having been a joomla dude for years, I have been using artisteer for about a month now and I think it's the best investment I ever made. It has a ton of module positions and now I don't have to search for any templates ever. I am looking for the down sides too. What's your opinion? add: I heard the seo wasn't as good, but I did a wp template on a a free host and has 2 comments in a few hours.
I use the program on my drupal sites, Ive found that the seo is just fine, My concern is more to do with some css style conflicts with certain modules, but for the most part it works great. There has been a few bugs but most have been fixed in the newer versions. Plus you can get free drupal themes at many different sites my favorite highlighted because they are mostly artisteer generated, ive added my own their. If your a drupal user you will find issues with panels sort of anyways. The css needs tweaked but its not that difficult.