Your question is a bit confusing, are you asking if it is effective to run a CPM campaign on a website with over 10K daily pageviews? Or are you asking if there are any CPM campaigns that are running on that scale?
sorry, meant to ask if any good CPM worth trying for sites with over 10K pageviews daily.. like will i make any money?
Well, it all depends on how much money you want to make. If you average at $0.30 CPM on a leaderboard, and $0.25 on a banner, both units placed site wide you effectivly earn $0.55CPM on your pageviews. With 10K pageviews daily that amounts to $5.50/day or $165/month. If you consider $165.00 as a monthly payoff worth the effort you would invest in the site then yes you can make money.