that's the thing, I don't want to test keywords - I don't write, or have website for adsense / SEO, I have it for readers....
It's definitely a YMMV type of thing. If I have a site on carpentry, though, I think ads for some new movie would look out of place...and people are on my site at the time for the purpose of carpentry, they are probably more in that mindset and more likely to click those ads than ads on some topic they visited a week ago.