I have an implimentation that I have no choice but to use Iframe. Is there any way that I can get it to work for me?
No, if you add adsense in Iframe, it is like you add adsense in a blank page with no site contents, that against the Tos.
Yeah, cheapez is right, its against the Tos to place your adsense in an Iframe.... My site was once in a situation where i put my adsense code in an Iframe to increase speed, and because the ad could not be correctly positioned on the page unless it was framed. I hadnt realized it was against the Tos and they contacted me about it.