I recently changed my webhost and my wordpress blog theme to allow more room for content. This has also led me to change my adsense ad placement and to reduce the amount. I have an ad unit on the left sidebar and the sidebar + a link unit on the sigle post pages. Any feedback is appreciated: http://www.celebridiot.com/gossip
I think its pretty good placement, however you could better integrate between posts on the front page and more in the content of posts in single pages.
on the main page i thought of trying to get an ad unit between like the 1st and 2nd pot and between the 5 and 6th but looking at the main index file I don't think I would know how to code it in. On the single page i can add a small ad unit in using my adsense deluxe plugin -- i will give that a try