Dating Dating is a huge niche. We’re born to do, essentially, one thing in life: find a mate. This is your turn to help others do this. Dating is a very accessible niche, yet very competitive. However, there are mini-niches in every single demographic and offer to match them. It also works well across almost any traffic source, especially social. The best way to get at dating is to be on top of new offers (or create your own) and to constantly rotate ads. Gaming Everyone needs a little entertainment, and whether at work, school or stuck at home, gaming is a simple choice to ease over a streak of boredom. You can opt for downloadable game affiliate offers, or online MMO game offers. I find the simple toolbar/downloadable game offers do great on Facebook. The key is making sure you are playing correctly with your targeting. Health This is a huge niche, and is more a collection of many niches put under this one category. Weight-loss, stop smoking, muscle-gain, and stress are all some examples of niches you can run. And again, like dating, it is very broad. Almost everyone has some health problems that you can target and get at. Find a demographic with a wide spread health related issue and target them for all they’re worth. I’d suggest a landing page with health niches, as many of the offer pages available to you do horrid jobs at preselling.
Make money online niche is definitely much bigger than gaming! Health is also one of my fav.. there are just so many you can work with once you break it down.
I agree with Justin that there are many profitable niches when it comes to affiliate marketing. Gaming is actually up and coming and a lot of the game guides on clickbank can be very profitable. Take the shokz guide for starcraft 2 for example.