The header needs to be customized so it's not so plain.. graphics in incorporated into the content area would look nice as well.
hmm... this is difficult to distinguish which where are ads and where is the real content. This could be good in some ways (I think this is intentional). Quite interesting.
Not really difficult, but blended in well to get a higher CTR. I would add a nice header image up the top as it looks too plain with too much of the light blue color being used.