On Wii - Formula 1 2009 using a F1 Steering Wheel Pack and on my Xbox 360 Assassins Creed II both are well descent titles and deserve a look, see link for reviews
well, mine is counter-strike... i think it will always be, its the best game of all time in its genre.
Too big a question to ask, I couldn't even narrow it down to my favourite on each console there are that many I love
I've never played CS and I think I may be the only person in the world who hasn't the way that my mates go on about it