Where is the hotel? What class of hotel is it? What type of amenities do they offer? What type of sight seeing or travel destinations are close by? All of these questions and many more should lead you to the answers you seek.
It depends on many factors such as what services you are providing, which geographical region you are targeting, what are your goals etc. After taking all this in account you can search your keywords.
Simple "hotel" + CityName + StateAbbv + CountryCode "hotels" + CityName + StateAbbv + CountryCode If you would like the rest or the above AdWords List, PM me. There are about 183K phrases.
You can target name of hotel, location of hotel, as well as long-tail local city information keywords.
Geo-targetting is the best for hotel, travel and real estate sites. Also target the keywords that are related to your customers.
make keywords like cheap accommodation, discount hotels, ... like wise... This is my small suggestion ...
for that niche you will definitely have alot of competition... go check out the google wonder wheel tool to find you some good longtails to optimize for.
It would probably be beneficial to you to use longtails along with geo targeting to get top positions... if you have top listings for longtails like that you are guaranteed to get some good targeted traffic.